Hey big boy!
- on your primary target - size or strength? Powerlifting or BB? Or powerbodybuilding
- on how often you work out!
If you want strength, do more sets with heavier weights and not to muscle failure, but more often. Like 5x5 for example.
If you're after size, use approx. the same weight and go for muscle failure (6-12 reps), do less sets, and less often. But i still recommend doing this more often than once per week, approx. 2 times per week or 3 times in 2 weeks.
Check out the "doggcrapp" program. It's a spin-off from HIT and i really like it. Google for it or wait, maybe it's here... www.intensemuscle.com
If you can't find it, i can explain that program to you if you're interested.